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1

Fatal Familial Insomnia: Clinical Aspects and Molecular Alterations

Llorens, Franc, Zarranz, Juan-José, Fischer, Andre, Zerr, Inga, Ferrer, Isidro

Journal:

Current Neurology and Neuroscience Reports

Année:

2017

Langue:

english

Fichier:

PDF, 936 KB

english, 2017

2

Central Apelin Controls Glucose Homeostasis via a Nitric Oxide-Dependent Pathway in Mice

Duparc, Thibaut, Colom, André, Cani, Patrice D., Massaly, Nicolas, Rastrelli, Sophie, Drougard, Anne, Le Gonidec, Sophie, Moulédous, Lionel, Frances, Bernard, Leclercq, Isabelle, Llorens-Cortes, Cathe

Journal:

Antioxidants & Redox Signaling

Année:

2011

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2011

3

Performances of the OVH magnetometer for the Danish Oersted satellite

Duret, D., Leger, J.M., Frances, M., Bonzom, J., Alcouffe, F., Perret, A., Llorens, J.C., Baby, C.

Journal:

IEEE Transactions on Magnetics

Année:

1996

Langue:

english

Fichier:

PDF, 396 KB

english, 1996

4

Altered Mitochondria, Protein Synthesis Machinery, and Purine Metabolism Are Molecular Contributors to the Pathogenesis of Creutzfeldt–Jakob Disease

Ansoleaga, Belén, Garcia-Esparcia, Paula, Llorens, Franc, Hernández-Ortega, Karina, Carmona Tech, Margarita, Antonio del Rio, José, Zerr, Inga, Ferrer, Isidro

Journal:

Journal of Neuropathology and Experimental Neurology

Année:

2016

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2016

5

Aging-related tau astrogliopathy (ARTAG): Not only tau phosphorylation in astrocytes

Ferrer, Isidro, Aguiló García, Meritxell, López González, Irene, Diaz Lucena, Daniela, Roig Villalonga, Aina, Carmona Tech, Margarita, Llorens, Franc, Garcia-Esparcia, Paula, Martinez-Maldonado, Aleja

Journal:

Brain Pathology

Année:

2018

Langue:

english

Fichier:

PDF, 2.69 MB

english, 2018

6

CSF nonphosphorylated Tau as a biomarker for the discrimination of AD from CJD

Ermann, Natalia, Lewczuk, Piotr, Schmitz, Matthias, Lange, Peter, Knipper, Tobias, Goebel, Stefan, Kornhuber, Johannes, Zerr, Inga, Llorens, Franc

Journal:

Annals of Clinical and Translational Neurology

Année:

2018

Langue:

english

Fichier:

PDF, 183 KB

english, 2018

7

Developmental analysis of Lingo-1/Lern1 protein expression in the mouse brain: Interaction of its intracellular domain with Myt1l

Franc Llorens, Vanesa Gil, Susana Iraola, Laura Carim-Todd, Eulàlia Martí, Xavier Estivill, Eduardo Soriano, José Antonio del Rio, Lauro Sumoy

Journal:

Developmental Neurobiology

Année:

2008

Langue:

english

Fichier:

PDF, 730 KB

english, 2008

8

The C-terminal domain of human grp94 protects the catalytic subunit of protein kinase CK2 (CK2α) against thermal aggregation : Role of disulfide bonds

Nerea Roher, Francesc Miró, Brigitte Boldyreff, Franc Llorens, Maria Plana, Olaf-Georg Issinger, Emilio Itarte

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 553 KB

english, 2001

9

Multiple platform assessment of the EGF dependent transcriptome by microarray and deep tag sequencing analysis

Franc Llorens, Manuela Hummel, Xavier Pastor, Anna Ferrer, Raquel Pluvinet, Ana Vivancos, Ester Castillo, Susana Iraola, Ana M Mosquera, Eva González, Juanjo Lozano, Matthew Ingham, Juliane C Dohm, Ma

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.52 MB

english, 2011

10

Proteomic analysis of SET-binding proteins

Jorge Vera, Josep M. Estanyol, Nuria Canela, Franc Llorens, Neus Agell, Emilio Itarte, Oriol Bachs, Montserrat Jaumot

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 431 KB

english, 2007

11

Cross talk between protein kinase CK2 and eukaryotic translation initiation factor eIF2β subunit

Franc Llorens, Stefania Sarno, Eduard Sarró, Anna Duarri, Nerea Roher, Flavio Meggio, Maria Plana, Lorenzo A. Pinna, Emilio Itarte

Journal:

Molecular and Cellular Biochemistry

Année:

2005

Langue:

english

Fichier:

PDF, 943 KB

english, 2005

12

Neurites regrowth of cortical neurons by GSK3β inhibition independently of Nogo receptor 1

Oscar Seira, Rosalina Gavín, Vanessa Gil, Franc Llorens, Alejandra Rangel, Eduardo Soriano, José Antonio Del Río

Journal:

Journal of Neurochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 753 KB

english, 2010

13

Unbalanced activation of ERK1/2 and MEK1/2 in apigenin-induced HeLa cell death

Franc Llorens, Francesc A Miró, Arnau Casañas, Nerea Roher, Lourdes Garcia, Maria Plana, Néstor Gómez, Emilio Itarte

Journal:

Experimental Cell Research

Année:

2004

Langue:

english

Fichier:

PDF, 755 KB

english, 2004

14

Persistent nuclear accumulation of protein kinase CK2 during the G1-phase of the cell cycle does not depend on the ERK1/2 pathway but requires active protein synthesis

Francesc A Miro, Franc Llorens, Nerea Roher, Maria Plana, Néstor Gómez, Emilio Itarte

Journal:

Archives of Biochemistry and Biophysics

Année:

2002

Langue:

english

Fichier:

PDF, 443 KB

english, 2002

15

The carboxy-terminal domain of Grp94 binds to protein kinase CK2α but not to CK2 holoenzyme

Nerea Roher, Stefania Sarno, Francesc Miró, Maria Ruzzene, Franc Llorens, Flavio Meggio, Emilio Itarte, Lorenzo A Pinna, Maria Plana

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 137 KB

english, 2001

16

Apigenin and LY294002 prolong EGF-stimulated ERK1/2 activation in PC12 cells but are unable to induce full differentiation

Franc Llorens, Lourdes Garcia, Emilio Itarte, Néstor Gómez

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 434 KB

english, 2002

17

PP1/PP2A phosphatases inhibitors okadaic acid and calyculin A block ERK5 activation by growth factors and oxidative stress

Lourdes Garcia, Fatima Garcia, Franc Llorens, Mercedes Unzeta, Emilio Itarte, Néstor Gómez

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 278 KB

english, 2002

18

PrP C regulates epidermal growth factor receptor function and cell shape dynamics in Neuro2a cells

Llorens, Franc, Carulla, Patricia, Villa, Ana, Torres, Juan M., Fortes, Puri, Ferrer, Isidre, del Río, José A.

Journal:

Journal of Neurochemistry

Année:

2013

Langue:

english

Fichier:

PDF, 829 KB

english, 2013

19

Microarray and deep sequencing cross-platform analysis of the mirRNome and isomiR variation in response to epidermal growth factor

Franc Llorens, Manuela Hummel, Lorena Pantano, Xavier Pastor, Ana Vivancos…

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 634 KB

english, 2013

20

Gene Expression Resulting from PrPCAblation and PrPCOverexpression in Murine and Cellular Models

Llorens, Franc, Ferrer, Isidre, Río, José Antonio

Journal:

Molecular Neurobiology

Année:

2014

Langue:

english

Fichier:

PDF, 426 KB

english, 2014

21

A highly expressed miR-101 isomiR is a functional silencing small RNA

Llorens, Franc, Bañez-Coronel, Mónica, Pantano, Lorena, del Río, Jose Antonio, Ferrer, Isidre, Estivill, Xavier, Martí, Eulàlia

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 498 KB

english, 2013

22

Complex Deregulation and Expression of Cytokines and Mediators of the Immune Response in Parkinson's Disease Brain is Region Dependent

Garcia-Esparcia, Paula, Llorens, Franc, Carmona, Margarita, Ferrer, Isidre

Journal:

Brain Pathology

Année:

2014

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2014

23

Sema3E/PlexinD1 regulates the migration of hem-derived Cajal-Retzius cells in developing cerebral cortex

Bribián, Ana, Nocentini, Sara, Llorens, Franc, Gil, Vanessa, Mire, Erik, Reginensi, Diego, Yoshida, Yutaka, Mann, Fanny, del Río, José Antonio

Journal:

Nature Communications

Année:

2014

Langue:

english

Fichier:

PDF, 3.14 MB

english, 2014

24

Subtype and regional regulation of prion biomarkers in sporadic Creutzfeldt-Jakob disease

Llorens, Franc, Zafar, Saima, Ansoleaga, Belén, Shafiq, Mohsin, Blanco, Rosi, Carmona, Marga, Grau-Rivera, Oriol, Nos, Carlos, Gelpí, Ellen, del Río, José Antonio, Zerr, Inga, Ferrer, Isidre

Journal:

Neuropathology and Applied Neurobiology

Année:

2015

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2015

25

PrP mRNA and protein expression in brain and PrP c in CSF in Creutzfeldt-Jakob disease MM1 and VV2

Llorens, Franc, Ansoleaga, Belén, Garcia-Esparcia, Paula, Zafar, Saima, Grau-Rivera, Oriol, López-González, Irene, Blanco, Rosi, Carmona, Margarita, Yagüe, Jordi, Nos, Carlos, del Río, José Antonio, G

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2013

26

Cerebrospinal fluid tau levels are a marker for molecular subtype in sporadic Creutzfeldt-Jakob disease

Karch, André, Hermann, Peter, Ponto, Claudia, Schmitz, Matthias, Arora, Amandeep, Zafar, Saima, Llorens, Franc, Müller-Heine, Annika, Zerr, Inga

Journal:

Neurobiology of Aging

Année:

2015

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2015

27

Neuroinflammatory Signals in Alzheimer Disease and APP/PS1 Transgenic Mice

López-González, Irene, Schlüter, Agatha, Aso, Ester, Garcia-Esparcia, Paula, Ansoleaga, Belen, LLorens, Franc, Carmona, Margarita, Moreno, Jesús, Fuso, Andrea, Portero-Otin, Manuel, Pamplona, Reinald,

Journal:

Journal of Neuropathology and Experimental Neurology

Année:

2015

Langue:

english

Fichier:

PDF, 6.40 MB

english, 2015

28

Creutzfeldt-Jakob Disease Subtype-Specific Regional and Temporal Regulation of ADP Ribosylation Factor-1-Dependent Rho/MLC Pathway at Pre-Clinical Stage

Zafar, Saima, Schmitz, Matthias, Younus, Neelam, Tahir, Waqas, Shafiq, Mohsin, Llorens, Franc, Ferrer, Isidre, Andéoletti, Olivier, Zerr, Inga

Journal:

Journal of Molecular Neuroscience

Année:

2015

Langue:

english

Fichier:

PDF, 7.04 MB

english, 2015

29

Cytokine profiles and the role of cellular prion protein in patients with vascular dementia and vascular encephalopathy

Schmitz, Matthias, Hermann, Peter, Oikonomou, Pantelis, Stoeck, Katharina, Ebert, Elisabeth, Poliakova, Tatjana, Schmidt, Christian, Llorens, Franc, Zafar, Saima, Zerr, Inga

Journal:

Neurobiology of Aging

Année:

2015

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2015

30

Involvement of PrPC in kainate-induced excitotoxicity in several mouse strains

Carulla, Patricia, Llorens, Franc, Matamoros-Angles, Andreu, Aguilar-Calvo, Patricia, Espinosa, Juan Carlos, Gavín, Rosalina, Ferrer, Isidre, Legname, Giuseppe, Torres, Juan Maria, del Río, José A.

Journal:

Scientific Reports

Année:

2015

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2015

31

Quantification of CSF biomarkers using an electrochemiluminescence-based detection system in the differential diagnosis of AD and sCJD

Llorens, Franc, Kruse, Niels, Schmitz, Matthias, Shafiq, Mohsin, da Cunha, José Eriton Gomes, Gotzman, Nadine, Zafar, Saima, Thune, Katrin, de Oliveira, João Ricardo Mendes, Mollenhauer, Brit, Zerr, I

Journal:

Journal of Neurology

Année:

2015

Langue:

english

Fichier:

PDF, 457 KB

english, 2015

32

Unraveling the neuroprotective mechanisms of PrP C in excitotoxicity

Llorens, Franc, del Río, José Antonio

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 762 KB

english, 2012

33

Increased albumin CSF/serum ratio in dementia with Lewy bodies

Llorens, Franc, Schmitz, Matthias, Gloeckner, Sara Friederike, Kaerst, Lisa, Hermann, Peter, Schmidt, Christian, Varges, Daniela, Zerr, Inga

Journal:

Journal of the Neurological Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 674 KB

english, 2015

34

Comparative analysis of cerebrospinal fluid biomarkers in the differential diagnosis of neurodegenerative dementia

Llorens, Franc, Schmitz, Matthias, Karch, André, Cramm, Maria, Lange, Peter, Gherib, Kerim, Varges, Daniela, Schmidt, Christian, Zerr, Inga, Stoeck, Katharina

Journal:

Alzheimer's & Dementia

Année:

2015

Langue:

english

Fichier:

PDF, 897 KB

english, 2015

35

Mitochondrial DNA differentiates Alzheimer from Creutzfeldt-Jakob disease

Podlesniy, Petar, Llorens, Franc, Golanska, Ewa, Sikorska, Beata, Liberski, Pawel, Zerr, Inga, Trullas, Ramon

Journal:

Alzheimer's & Dementia

Année:

2016

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2016

36

CSF biomarkers in neurodegenerative and vascular dementias

Llorens, Franc, Schmitz, Matthias, Ferrer, Isidro, Zerr, Inga

Journal:

Progress in Neurobiology

Année:

2016

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2016

37

Identification of new molecular alterations in Fatal Familial Insomnia

Llorens, Franc, Thüne, Katrin, Schmitz, Matthias, Ansoleaga, Belén, Frau-Méndez, Margalida A., Cramm, Maria, Tahir, Waqas, Gotzmann, Nadine, Berjaoui, Sara, Carmona, Margarita, Silva, Christopher J.,

Journal:

Human Molecular Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 3.02 MB

english, 2016

38

Hereditary Human Prion Diseases: an Update

Schmitz, Matthias, Dittmar, Kathrin, Llorens, Franc, Gelpi, Ellen, Ferrer, Isidre, Schulz-Schaeffer, Walter J., Zerr, Inga

Journal:

Molecular Neurobiology

Année:

2016

Langue:

english

Fichier:

PDF, 2.90 MB

english, 2016

39

Application of capillary immunoelectrophoresis revealed an age- and gender-dependent regulated expression of PrPC in liver

Arora, Amandeep Singh, Zafar, Saima, Kollmar, Otto, Llorens, Franc, Tahir, Waqas, Vanselow, Sven, Kumar, Prateek, Schmerr, Mary Jo, Schmitz, Matthias, Zerr, Inga

Journal:

ELECTROPHORESIS

Année:

2015

Langue:

english

Fichier:

PDF, 844 KB

english, 2015

40

Investigating the behaviour of a small Mediterranean catchment using three different hydrological models as hypotheses

Ruiz-Pérez, G., Medici, C., Latron, J., Llorens, P., Gallart, F., Francés, F.

Journal:

Hydrological Processes

Année:

2016

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2016

41

Fatal familial insomnia: Mitochondrial and protein synthesis machinery decline in the mediodorsal thalamus

Frau-Méndez, Margalida A., Fernández-Vega, Iván, Ansoleaga, Belén, Blanco, Rosa, Carmona, Margarita, Antonio del Rio, Jose, Zerr, Inga, Llorens, Franc, Zarranz, Juan José, Ferrer, Isidro

Journal:

Brain Pathology

Année:

2016

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2016

42

Eukaryotic translation-initiation factor eIF2β binds to protein kinase CK2: effects on CK2α activity

LLORENS, Franc, ROHER, Nerea, MIRÓ, Francesc A., SARNO, Stefania, RUIZ, F. Xavier, MEGGIO, Flavio, PLANA, Maria, PINNA, Lorenzo A., ITARTE, Emilio

Journal:

Biochemical Journal

Année:

2003

Langue:

english

Fichier:

PDF, 298 KB

english, 2003

43

The N-terminal domain of the human eIF2β subunit and the CK2 phosphorylation sites are required for its function

Llorens, Franc, Duarri, Anna, Sarró, Eduard, Roher, Nerea, Plana, Maria, Itarte, Emilio

Journal:

Biochemical Journal

Année:

2006

Langue:

english

Fichier:

PDF, 527 KB

english, 2006

44

Cerebrospinal α-synuclein in α-synuclein aggregation disorders: tau/α-synuclein ratio as potential biomarker for dementia with Lewy bodies

Llorens, Franc, Schmitz, Matthias, Varges, Daniela, Kruse, Niels, Gotzmann, Nadine, Gmitterová, Karin, Mollenhauer, Brit, Zerr, Inga

Journal:

Journal of Neurology

Année:

2016

Langue:

english

Fichier:

PDF, 490 KB

english, 2016

45

Reelin Expression in Creutzfeldt-Jakob Disease and Experimental Models of Transmissible Spongiform Encephalopathies

Mata, Agata, Urrea, Laura, Vilches, Silvia, Llorens, Franc, Thüne, Katrin, Espinosa, Juan-Carlos, Andréoletti, Olivier, Sevillano, Alejandro M., Torres, Juan María, Requena, Jesús Rodríguez, Zerr, Ing

Journal:

Molecular Neurobiology

Année:

2016

Langue:

english

Fichier:

PDF, 3.80 MB

english, 2016

46

The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases

Schmitz, Matthias, Cramm, Maria, Llorens, Franc, Müller-Cramm, Dominik, Collins, Steven, Atarashi, Ryuichiro, Satoh, Katsuya, Orrù, Christina D, Groveman, Bradley R, Zafar, Saima, Schulz-Schaeffer, Wa

Journal:

Nature Protocols

Année:

2016

Langue:

english

Fichier:

PDF, 631 KB

english, 2016

47

Evaluation of α-synuclein as a novel cerebrospinal fluid biomarker in different forms of prion diseases

Llorens, Franc, Kruse, Niels, Schmitz, Matthias, Gotzmann, Nadine, Golanska, Ewa, Thüne, Katrin, Zejneli, Orgeta, Kanata, Eirini, Knipper, Tobias, Cramm, Maria, Lange, Peter, Zafar, Saima, Sikorska, B

Journal:

Alzheimer's & Dementia

Année:

2016

Langue:

english

Fichier:

PDF, 697 KB

english, 2016

48

Stratification by Genetic and Demographic Characteristics Improves Diagnostic Accuracy of Cerebrospinal Fluid Biomarkers in Rapidly Progressive Dementia

Karch, André, Llorens, Franc, Schmitz, Matthias, Arora, Amandeep Singh, Zafar, Saima, Lange, Peter, Schmidt, Christian, Zerr, Inga

Journal:

Journal of Alzheimer's Disease

Année:

2016

Langue:

english

Fichier:

PDF, 82 KB

english, 2016

49

Application of an in vitro-amplification assay as a novel pre-screening test for compounds inhibiting the aggregation of prion protein scrapie

Schmitz, Matthias, Cramm, Maria, Llorens, Franc, Candelise, Niccolò, Müller-Cramm, Dominik, Varges, Daniela, Schulz-Schaeffer, Walter J., Zafar, Saima, Zerr, Inga

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 750 KB

english, 2016

50

Molecular Alterations in the Cerebellum of Sporadic Creutzfeldt–Jakob Disease Subtypes with DJ-1 as a Key Regulator of Oxidative Stress

Tahir, Waqas, Zafar, Saima, Llorens, Franc, Arora, Amandeep Singh, Thüne, Katrin, Schmitz, Matthias, Gotzmann, Nadine, Kruse, Niels, Mollenhauer, Brit, Torres, Juan Maria, Andréoletti, Olivier, Ferrer

Journal:

Molecular Neurobiology

Année:

2016

Langue:

english

Fichier:

PDF, 3.33 MB

english, 2016